9 Best Gaming Mouse with Side Buttons to Buy in 2022

Gaming is something that everyone enjoys. Fortunately, with advanced technology, games and gaming gadgets keep getting better with time. So, for the best gaming experience, a simple mouse with two buttons and a scroll wheel might not be enough. And for that, you might have to up your mouse game and get yourself a good gaming mouse with side buttons.

A gaming mouse with programmable side buttons will enhance your gaming experience. Since you no longer have to memorize hotkeys and panic right in the middle of the game to recall it. On top of that, no matter what game you play, you can always program side buttons as per the need of the respective game.

Here we have compiled a list of 9 best gaming mice with side buttons popular with gamers. As the name itself shows, a gaming mouse is specially designed for the game and is equipped with features to improve your gaming experience.

Keep reading to find more about the curated list of the best gaming mouse with side buttons that will improve your gaming experience.

9 Best Gaming Mouse with Side Buttons to Buy in 2022

1. Logitech G502

logitech g502 best gaming mouse with side buttons

The first place on our list of the best gaming mouse with side buttons is the Logitech G502 high-performance gaming mouse, as it comes with several programmable buttons. Logitech has been around for a while and is primarily known for providing the PC gaming community with revolutionary peripherals.

This Logitech gaming mouse comprises 11 buttons along with the two standard thumb buttons. Thus, assign custom commands to the buttons and save up to five ready-to-play profiles directly to the mouse. Besides this, its adjustable weight system lets you arrange up to five removable 3.6 grams weights inside the mouse for customized balance tuning.

Similarly, a metal spring tensioning system & pivot hinges are built into left, and right gaming mouse buttons for a crisp and clean click feel. And through its programmable Lightsync and RDB Lighting technology, you can customize lighting from precisely 16.8 million colors to match your team’s color. Although the Logitech mouse comes in two variants – wired and wireless- both offer the same features.

Reason to buy:

  • Solid construction.
  • Good button placement.
  • Adjustable weight system.
  • 11 Programmable button options.
  • 5,600 max dpi sensitivity plus zero smoothing.

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2 Redragon M602

Redragon M602

Redragon M602 is an incredible wired gaming mouse that is specially built for gaming computers. The ergonomic shape delivers a highly comfortable and precise experience for PC gamers. Although this ergonomic Redragon is quite heavy, the finger rest grips on the right side are better than any other mouse.

Its high-precision sensor delivers pinpoint accuracy. While the gaming-grade micro switches ensure outstanding durability, longevity, and extreme responsiveness, thus providing you an even greater edge over your competition.

For buttons, it has 7 MMO user-programmable buttons. And has 5 memory profiles, each with a different LED color option for instant identification. This Redragon M602 Gaming Mouse offers you total personalization for your gaming computer or gaming laptop by considering all these things.

Reason to Buy

  • Several RGB settings and solid build quality.
  • Up to 7200 DPI.
  • 10G acceleration.
  • Anti-Skid Scroll Wheel.
  • TEFLON feet pads for ultimate gaming control.

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3. Razer DeathAdder Essential

Razer DeathAdder Essential

Tailor your gaming experience with the DeathAdder Essential from Razer. The Razer DeathAdder Essential is one of the best gaming mouse with side buttons in the market in terms of performance. What makes it more incredible is its high-precision 6,400 DPI optical sensor that offers on-the-fly sensitivity through dedicated DPI buttons on the mouse.
Not only that, it even lets you adjust the brightness of the LED. And the mouse is very solid with remarkable quality. Its scroll wheel has small, tactile bumps that enhance grip and allow more controlled scrolling in high-stakes gaming situations.

The mouse’s side buttons are in a perfect position, which helps prevent accidental triggering and offers ease to reach and use. Furthermore, its five programmable buttons allow button remapping and assignment of complex macro functions via Razer Synapse.

Reason to Buy

  • Dedicated DPI buttons with sensitivity adjustment.
  • Rubberized Scroll Wheel for Maximum Accuracy.
  • 5 Programmable Buttons.
  • High-Precision 6,400 DPI Optical Sensor.

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4. UtechSmart Venus Gaming Mouse

UtechSmart Venus Gaming Mouse

UtechSmart Venus Gaming Mouse can be a fantastic choice for those who want a good quality product but are on a tight budget. It is the best gaming mouse with 12 side buttons and comes with a better sensor than any gaming mouse listed in this article. This gaming mouse with side buttons is specially created for MMO gaming, giving its excess of buttons.

Similarly, it has an adjustable sensitivity level, ranging from 200 to 16400, built right into the gaming mouse. And you can easily adjust the sensitivity by using the buttons on the mouse. It also has a unique setting switch button on the bottom of the mouse that lets you perform the switch profile command with maximum efficiency.

All the macro buttons let you customize the functions to your requirements and can be seamlessly mapped to any of the usual keyboard keys combinations. Finally, the mouse is covered with a matte finish that avoids hand sweat & slippery, and the weight is pretty adjustable.

Reason to Buy

  • Auto Fire button.
  • Adjustable weighted mouse.
  • Multiple programmable 12 side buttons.
  • Up to 16400 DPI.
  • Adjustable mouse sensitivity.

Reason to Avoid

  • Buggy software; issue with automatic updates.

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5. Razer Naga Trinity Gaming Mouse

Razer Naga Trinity Gaming Mouse

If you love modular designs, then the Razer Naga Trinity Gaming Mouse can be the best choice for you. It comes with three interchangeable plates (or modules) that you can replace for your gaming need. Each module is designed to suit a different kind of gameplay. You switch between a standard two-button, six-button, and twelve-button layout.

Having these extra buttons to assign functionality to is an amazing feature for gamers. And being one of the best gaming mice with side buttons, this device fulfills the title and offers complete modular customizability.

Moreover, its customizable Chroma RGB color profiles support over 16.9 million combinations with pre-set profiles comprised as a bonus for the user. It also offers a 1600 customizable DPI and a USB refresh rate of 1000hz. And the finish of this gaming mouse is amazing and feels incredibly good in your hands.

Reason to Buy

  • Up to 19 Programmable Buttons.
  • Customizable Chroma RGB Color Profiles.
  • High-Precision 16,000 DPI Optical Sensor.
  • 3 interchangeable side plates with 2, 7, and 12-button configurations.

Reason to Avoid

  • The mouse is a bit heavy and uncomfortable at times.

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6. Razer DeathAdder Elite

Razer DeathAdder Elite

Want to have the best ergonomic design for a gaming mouse? Well, the Razer DeathAdder Elite can be the perfect choice for you! Its ergonomic design makes the mouse really comfortable and even ideal for long gaming sessions. Also, it has seven buttons, including two buttons present below the scroll wheel and two side buttons, which are entirely unremarkable.

These programmable buttons bring amazing functionality, as well as have incredible quality. Besides this, the Razer DeathAdder Elite gaming mouse offers 16000 personalized DPI making this mouse appropriate for almost every type of game. Also, its rigid, rubberized scroll wheel offers maximum accuracy by increasing grip for more controlled scrolling in high-stakes gaming circumstances.

If you are wondering whether its performance is excellent or not, you don’t have to worry about it at all. Because performance-wise, it is remarkable, something which many users on Amazon have stated. As a result, these features make this the best gaming mouse with side buttons.

Reason to Buy

  • Customizable Chroma RGB Lighting.
  • High-Precision 16,000 DPI Optical Sensor.
  • Durable Mechanical Switches.
  • Rubberized Scroll Wheel for Maximum Accuracy.

Reasons to Avoid

  • Buggy software; Razer Synapse software logs out users often.

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7. Logitech G600

Logitech G600

Do you love MMO games? If your answer is yes, then the Logitech G600 MMO gaming mouse is designed just for you! It has 12 mechanical side buttons and is designed for a quick & no-look navigation gaming experience.

And the low friction polytetrafluoroethylene feet prevent friction on nearly any surface for precise cursor movements, smoother motions, and enhanced accuracy. One of the fantastic features it offers is the ‘G Shift’ ring finger button that instantly doubles the number of actions you can perform with each button.

With this complete personalized mouse, you can set up your way with customizable thumb panel lighting colors, DPI levels, and button assignments. Moreover, its sculpted shape and tuned buttons reduce click fatigue during marathon multiplayer sessions.

Reason to Buy

  • 20 MMO tuned buttons.
  • G shift ring finger button.
  • G8 cycle modes with customizable DPI values, up to 8200.
  • Complete personalization.

Reason to Avoid

  • The mouse is heavy.

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8. SteelSeries Sensei 310

SteelSeries Sensei 310

The Steelseries Sensei 310 is the best gaming mouse for those looking for a fully ambidextrous mouse. Its shape offers flexibility and comfort due to an ultradurable pure silicon grip on the sides for a durable action. Similarly, the textured grips on the thumb rest and the scroll will assist you in tackling the mouse better.

Not to mention, all the buttons are programmable depending on your requirements. Besides, you can experience the exclusive TrueMove3 sensor, praised for its precise tracking, performance, and most natural mouse movements.

What makes this mouse more amusing is its weight! It only weighs a total of just 92g, which is lower than most of the gaming mice listed in this article. Although it has a maximum DPI of up to 12,000, it only comes with two DPI settings, as well as there’s only one toggle that allows you to switch between these settings. Yet, this technology makes this ambidextrous mouse the best gaming mouse with side buttons.

Reasons to Buy

  • Ambidextrous design.
  • Has 8 programmable buttons.
  • Lightweight gaming mouse.
  • Split-trigger buttons give fast and consistent clicks.

Reasons to Avoid

  • Only two customizable DPI settings.
  • A substandard mouse cord might get damaged during extreme gameplay.

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9. Redragon M908

Redragon M908

Lastly, we have Redragon M908 Impact on our list, which is probably the heaviest gaming mouse. Nevertheless, it is also the most versatile gaming mice that are mentioned in our list. It has five profiles that you can save and quickly load from as you play.

And it comprises twelve programmable side buttons, making it easier to switch between in-game spells and inventory. Besides, you also get a left mouse click button. Moreover, it is designed with up to 12400 DPI and five adjustable DPI levels to meet your multiple requirements, be it for daily work or gaming.

Its adjustable DPI can be easily adjusted by plus or minus 100 from 100 to 12400 through the gaming mouse software. The five memory profiles mentioned above have a dedicated light color for quick identification. Also, the 8-piece weight tuning set is easy to alter the weight to suit your games.

Reason to Buy

  • It is designed with up to 12400 DPI and 5 adjustable DPI levels.
  • RGB Backlight & Programmable Buttons.
  • Features 8 buttons and 12 MMO programmable side buttons.

Reason to Avoid

  • Its weight is quite heavy when compared to other mice.

Check Price on Amazon

Wrapping UP: Best Gaming Mouse with Side Buttons!

So, this is the list of the best gaming mouse with side buttons that are famous among the gaming community. Choosing the best gaming mouse depends on your preferred gaming style and the features it offers.

The side buttons on a mouse can significantly enhance a gamer’s performance by adding all the required adjusted settings right at their thumbs, such as the DPI settings and other in-game commands.

If you are a newcomer to the PC gaming world, you might think about the term DPI. Well, it is the short form for “dots per inch” to specify how sensitive your mouse is. The higher the number, the wider the range. Therefore it is crucial to look at the DPI value while shopping for a gaming mouse.

And with a lot of gaming mice out there, it can be the best choice to pick up the best mouse based on the DPI settings, weight, and the number of side buttons. We have also written a guide on the best ergonomic mouse pads that you can buy to complement your mouse, do check that out.

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